High-Protein Tuna Salad Lettuce Cups

Featured in: Fun & Easy Meals

Fresh tuna salad gets a healthy upgrade with Greek yogurt and crisp butter lettuce cups. This protein-packed dish combines canned tuna with light mayo, Dijon mustard, diced celery, red onion, and fresh parsley for a creamy, flavorful filling. Each serving delivers 24g of protein while staying light at just 185 calories.

The assembly is effortless—mix the ingredients, season to taste, and spoon into washed lettuce leaves. Add avocado, cherry tomatoes, and shredded carrots for extra crunch and nutrients. Perfect for meal prep, these cups hold up well for hours and taste even better when flavors meld.

Updated on Tue, 10 Feb 2026 13:16:00 GMT
Crisp butter lettuce cups filled with fresh High-Protein Tuna Salad, topped with cherry tomatoes and avocado. Save
Crisp butter lettuce cups filled with fresh High-Protein Tuna Salad, topped with cherry tomatoes and avocado. | kookycrunch.com

There's something about a lunch that doesn't require heating anything up—no microwave beeping, no stovetop chaos—that felt revolutionary when I first discovered tuna salad lettuce cups. I was standing in my kitchen on a Tuesday afternoon, staring at a can of tuna and some wilted lettuce, thinking there had to be something better than my usual sandwich routine. That first bite, with the cool crunch of butter lettuce giving way to creamy, lemony tuna, changed how I thought about eating light without feeling deprived.

I packed these for a hiking trip last summer, and my friend couldn't believe how filling something so light could be. We ate them sitting on a rock overlooking the valley, and she asked for the recipe before we'd even finished—that's when I knew this wasn't just another salad, it was something people actually wanted to make again.

Ingredients

  • Tuna in water, drained: The foundation of everything—look for solid or chunk varieties depending on your texture preference, and always drain it well or your salad becomes a soggy mess.
  • Greek yogurt: This is your secret weapon for creaminess without heaviness; the tanginess plays beautifully against the lemon and mustard.
  • Light mayonnaise: A modest tablespoon gives richness without overwhelming the cleaner flavors you're building.
  • Dijon mustard: One teaspoon is enough to brighten everything and add sophistication that plain mayo never could.
  • Celery and red onion: The crunch and bite here are non-negotiable; don't skip the dicing—small pieces mean the flavors distribute evenly in every bite.
  • Fresh parsley: This keeps the salad from tasting canned and old; dried herbs won't give you the same fresh snap.
  • Lemon juice: The final magic that prevents the mixture from tasting flat or fishy.
  • Butter lettuce or romaine leaves: Butter lettuce is more delicate and elegant, but romaine holds the filling without tearing if you're less gentle with assembly.
  • Avocado, tomatoes, and carrots: These toppings are where you add color, texture, and the nutrition that makes this feel like a complete meal instead of just protein.

Instructions

Product image
Ideal for slow-simmered sauces, braised vegetables, baked dips, and cozy one-pot meals with even heat.
Check price on Amazon
Combine the tuna base:
In a medium bowl, mix your drained tuna with the Greek yogurt, mayonnaise, and Dijon mustard first—this creates your creamy foundation. Then fold in the celery, red onion, and parsley, stirring gently so everything stays mixed but the vegetables don't get crushed into mush.
Balance the seasoning:
Squeeze that lemon juice in and taste as you go, adding salt and pepper until it tastes bright and alive. Trust your palate here—you might need less salt if your mustard and yogurt are already salty enough.
Prepare your lettuce canvas:
Lay out your lettuce leaves on a clean plate or cutting board, making sure they're completely dry so they stay crisp. If they're wet, the tuna salad will soften them faster than you'd like.
Build with intention:
Spoon a generous portion of tuna salad into each leaf, leaving a little room at the edges so you can still pick them up without everything spilling out. This is where it stops being just ingredients and becomes something you actually want to eat.
Crown with freshness:
Arrange avocado slices, cherry tomato halves, and shredded carrots on top of each cup, pressing them gently into the salad so they stay put. The color and texture here matter—they're not just garnish, they're essential to every bite.
Serve right away:
These are best eaten immediately while everything is still cold and crisp, though you can keep the tuna salad separate from the lettuce for a few hours if you're meal prepping.
Product image
Ideal for slow-simmered sauces, braised vegetables, baked dips, and cozy one-pot meals with even heat.
Check price on Amazon
Freshly made High-Protein Tuna Salad Lettuce Cups garnished with parsley and lemon, served on a light lunch plate. Save
Freshly made High-Protein Tuna Salad Lettuce Cups garnished with parsley and lemon, served on a light lunch plate. | kookycrunch.com

My mom tried this once thinking it was too simple to be good, then made it twice the next week. There's something about meals this straightforward and honest that remind you that fancy doesn't always mean better.

How to Make It Your Own

I've learned that this salad is almost impossible to mess up once you understand the basic formula. The tuna stays the same, but everything else is up for interpretation based on what you have and what sounds good that day. Some mornings I add crispy bacon bits, other times I'll throw in capers or a tiny bit of pickle relish for briny richness.

Why This Works as a Weight Loss Meal

The protein in the tuna and Greek yogurt keeps you full for hours, which is the real secret to any successful light meal—satiation, not deprivation. The lettuce cups give you volume and crunch without calories, and the healthy fats from avocado actually help you absorb nutrients and stay satisfied between meals.

Storage and Make-Ahead Tips

I keep the tuna salad in a glass container in the fridge for up to three days, which means you can eat this three days in a row if you want. Just remember to pack the lettuce leaves separately if you're bringing this to work, or they'll turn into sad, wet paper by lunchtime.

  • Store the tuna salad in an airtight container and prep fresh lettuce cups right before eating for maximum crunch.
  • If you want to meal prep these, keep all components separate and assemble each one fresh when you're ready to eat.
  • The avocado is best added just before eating since it browns quickly, but the rest of the salad holds up beautifully for days.
Product image
Mix doughs, batters, and whipped cream easily for baking cakes, cookies, and everyday treats.
Check price on Amazon
Easy High-Protein Tuna Salad in crunchy lettuce cups, topped with shredded carrots and halved cherry tomatoes for serving. Save
Easy High-Protein Tuna Salad in crunchy lettuce cups, topped with shredded carrots and halved cherry tomatoes for serving. | kookycrunch.com

This is the kind of meal that becomes a habit without feeling like a sacrifice, which is exactly when you know you've found something worth keeping. Make it once, and you'll find yourself craving it on afternoons when you need something that tastes good and makes you feel strong.

Recipe FAQ

Can I make this ahead of time?

Yes, prepare the tuna mixture up to 24 hours in advance and store refrigerated. Fill lettuce cups just before serving to prevent wilting.

What lettuce works best for cups?

Butter lettuce, Boston bibb, or romaine leaves work perfectly. Choose large, pliable leaves that form natural cups without tearing.

Is this suitable for meal prep?

Absolutely. Store tuna salad and lettuce separately in airtight containers. Assemble when ready to eat for best texture and freshness.

Can I use canned tuna in oil?

Tuna packed in water keeps this lighter, but oil-packed tuna adds richness. Drain well and reduce mayo slightly if using oil-packed variety.

How do I make it dairy-free?

Replace Greek yogurt with additional light mayonnaise or dairy-free yogurt alternative. The texture remains creamy without dairy.

What other toppings work well?

Cucumber slices, radishes, chopped hard-boiled eggs, crumbled feta, or sliced jalapeños add flavor and texture contrast.

High-Protein Tuna Salad Lettuce Cups

Protein-rich tuna salad in crisp lettuce cups—ready in 15 minutes for a light, satisfying meal.

Prep duration
15 min
0
Complete duration
15 min
Created by Jake Peterson


Skill level Easy

Heritage American

Output 2 Portions

Diet considerations No gluten, Low-Carbohydrate

Components

Tuna Salad

01 1 can (5 oz) tuna in water, drained
02 2 tablespoons nonfat or low-fat Greek yogurt
03 1 tablespoon light mayonnaise
04 1 teaspoon Dijon mustard
05 1 celery stalk, finely diced
06 ¼ small red onion, finely diced
07 1 tablespoon fresh parsley, chopped
08 Juice of ½ lemon
09 Salt and pepper to taste

Lettuce Cups & Toppings

01 1 small head butter lettuce or romaine, leaves separated, washed and dried
02 ½ avocado, sliced (optional)
03 8 cherry tomatoes, halved
04 2 tablespoons shredded carrots (optional)

Directions

Phase 01

Prepare Tuna Mixture: In a medium bowl, combine the drained tuna, Greek yogurt, mayonnaise, Dijon mustard, celery, red onion, parsley, and lemon juice. Mix thoroughly until well combined.

Phase 02

Season Salad: Season the tuna salad with salt and pepper to taste, adjusting seasonings as needed.

Phase 03

Arrange Lettuce Cups: Arrange the lettuce leaves on a serving plate to form individual cups.

Phase 04

Fill Cups: Spoon the tuna salad evenly into each lettuce cup.

Phase 05

Add Toppings: Top each cup with avocado slices, cherry tomato halves, and shredded carrots if desired.

Phase 06

Serve: Serve immediately while lettuce remains crisp and fresh.

Necessary tools

  • Medium mixing bowl
  • Spoon or fork
  • Sharp knife
  • Cutting board

Allergy details

Review each component carefully for potential allergens and consult with healthcare professionals if you're uncertain about any ingredient.
  • Contains fish (tuna)
  • Contains egg (mayonnaise)
  • Contains dairy (Greek yogurt)

Nutrient breakdown (per portion)

These values are estimates only and shouldn't replace professional medical guidance.
  • Energy: 185
  • Fats: 7 g
  • Carbohydrates: 7 g
  • Proteins: 24 g